St. John’s Wort is a widely known herbal remedy for depression, which has been used for millennia. This plant is very interesting as a neuroenhancer as it has a desirable profile of psychotropic effects, has been identified in a broad review of studies as superior to placebo, and is available in most parts of the world legally over the counter.
In the eyes of some, St. John’s Wort may bear additional appeal for being natural and non-refined. We would like to mention that attributes such as natural, non-processed, or organic do not equate with safe, reliable, or good. Herbal medicines are often referred to by the plant’s name and administered as such simply because the active ingredients are not accurately identified. To the serious researcher and the informed consumer this should be a reason for additional scrutiny rather than a word of praise.